Composition
Aluminium Hydroxide – 291 mg
Magnesium Hydroxide – 98 mg
Oxetacaine – 10 mg
Packing
170 ml Bottle
Product Description
Cidken gel contains Oxetacaine, Aluminium Hydroxide and magnesium hydroxide.
Oxetacaine is a local anesthetic. It is used orally for management of the hemorrhoid pain and relief associated with peptic ulcer disease.
Aluminium Hydroxide is naturally occurring mineral gibbsite. Gibbsite is a typically metal hydroxide structure with hydrogen bonds. It has double layer of hydroxyl groups. It is amphoteric and dissolves acid and neutralizes it.
Magnesium hydroxide is an organic compound which is called as milk of magnesia because of its appearance. It is a component of antacids and laxatives. It is having low solubility in water and causes interference with the absorption of folic acid and iron.
Indication
- Hyperacidity
- GERD
- Peptic ulcer
- Hemorrhoid pain
- Gastric / Duodenal ulcer
- Stomach discomfort
- Local anesthetic
- Hurt burn in late pregnancy
- Eructation
Mechanism of action
Oxetacaine produces the reversible loss of sensation by blocking the conduction of nerve impulse. This causes decrease in permeability of sodium ions across the membrane in stomach. It increases the stomach pH and causes relief in hyperacidity. The presence of aluminium hydroxide and magnesium hydroxide reacts chemically to neutralize the acid by forming the coating over the inflamed mucosa.
Pharmacology
Absorption
The drug after administration reduces the acid in the stomach. The adhering property of aluminum and magnesium as vehicle with drug preparation causes oxetacaine to cause topical anesthetic action. Very small amount of aluminum and magnesium is absorbed by the bowel.
Distribution
It produces local action in presence of acid
Excretion
The absorbed form is excreted in urine
Contraindications
- Low level of phosphate in blood
- Renal impairment
Precautions
- Not to used for prolonged period of time can cause hypophosphatemia
- Not used in hypersensitivity to any drug
- Nausea
- Vomiting