Flucide kit 2018-05-18T10:17:45+00:00

Fluconazole   –   150 mg

Azithromycin   –   1000 mg

Ornidazole   –   750 mg

Each box contain 1 Blister strip of 1 tablet of Fluconazole, 1 tablet of Azithromycin and 2 tablet of Ornidazole.

Flucide- Kit contains 1 tablet of fluconazole, 1 tablet of Azithromycin, 2 tablets of Ornidazole.  Azithromycin is an azalide, with a sub-class of macrolide antibiotic. It is obtained from erythromycin, nitrogen atom with methyl-substitution which is incorporated to lactone ring. Azithromycin is effective against most bacterial infections than erythromycin. Ornidazole is a drug that used to cure protozoan infections. It is used for Crohn’s disease after bowel resection.

  • Reduces drug-resistance bacteria
  • Maintains effectiveness of drug
  • Mild to moderate infections
  • Non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis
  • STD (Sexually transmitted diseases)
  • Bacterial infections caused by Mycobacterium

The kit contains   Fluconazole:   Anti-fungal

Azithromycin:  Anti-bacterial

 Ornidazole:      Anti-protozoan            

The combi-kit shows its action in three ways as it provides three way protections as anti-fungal, anti-bacterial and anti-protozoal. Antifungal drugs causes CIDAL by killing the fungal organism and causes fewer side effects to the host organism. Antibacterial drug produces its action by inhibition of cell wall synthesis, nucleic acid metabolism and thereby protein synthesis. This causes the destruction of destruction of bacterial cell. Antiprotozoal drug causes interference with metabolism processes, interference with reproduction, larval physiology and neuromuscular physiology of parasite.

Pharmacology

Absorption

After oral administration it is well absorbed into the body fluids.

Distribution

It gets widely distributed in the body with a large volume of distribution. It undergoes a significant metabolism.

Excretion

The excretion of the drug is through urine.

Absorption

After oral administration it is well distributed in the body. The pharmacokinetic profile of fluconazole distinguishes it from anti-fungal agent as the bioavailability of the drug is more than 90%. The plasma protein binding of the drug is 12%.

Distribution

The volume of distribution of the drug is throughout the body fluids. The peak concentration attains according to dose. The drug is metabolically stable.

Excretion

It is excreted as metabolite. The route of elimination is renal. 11% of the drug is excreted through kidney.

  • Contraindicated in patients with hypersensitive action
  • Hypersensitivity to nitroimidazole derivatives
  • Overdose reactions
  • Hepatic dysfunction
  • Concomitant use of fluconazole and quinidine
  • During first trimester of pregnancy
  • Can pass through human milk
  • Severe or lethal hepato-toxicity
  • Serious cardiac arrhythmias
  • Renal and hepatic impairment
  • CNS diseases
  • Impairs the ability for mechanical work

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