Composition
Methylcobalamin – 1500 mcg
Alpha Lipoic Acid – 100 mg
Folic Acid – 1.5 mg
Pyridoxin HCl – 3 mg
Packing
Each box contain 3 Alu-Alu strips of 10 capsules
Product Description
Nervoba Ala contains methylcobalamin, alpha lipoic acid, folic acid and pyridoxine phosphate.
MethylcobalaminIt is a form of vitaminB12. It is a cobalamin which differs from cyanocobalamin. The cyanide group is replaced by methyl group in methylcobalamin. Octahedral cobalt III is present in the centre.
Alpha lipoic acidIt is an antioxidant and is used for diabetes and nerve-related synmptomsof diabetes including burning, pain, and numbness in the legs and arms. High doses of alpha-lipoic acid are approved in Germany for the treatment of these symptoms.
Folic acidIt is also called as folate which is B vitamin. It is mainly used in food supplement industry. When administered in the body it is converted to dihydrofolate to tetrahydrofolate and to its derivatives.
Pyridoxine phosphateIt is a form of vitamin B6
Indication
- Neuropathic pain
- Anxiety disorder
- Reduces the haemocysteine levels
- Reduce the risk of atheriosclerosis
- Prevent LDL concentration
- Prevents induction of DNA damage
- Insomnia
- Skin disorders
- Diabetic nerve pain
Mechanism of action
MethylcobalaminIt is the active form of vitamin B12 which a water soluble vitamin. It functions as to transfer methyl group for the regeneration of methionine from homocysteine. It acts as a cofactor for enzyme methionin synthase. In cases of anemia it causes the production of erythrocytes by nucleic acid synthesis in bone marrow.
Pharmacology
Methycobalamin
AbsorptionThe drug is well absorbed in the body with peak concentration achieved after 3hrs.
DistributionAfter oral administration it is well distributed
ExcretionThe drug is excreted through urine.
Contraindications
- Decreases the GI absorption with neomycin
- Reduces the serum concentrations of oral contraceptives
Precautions
- Polycythemia rubra vera
- Megaloblastic anemia
- Cobalt or cobalamin allergy
- Leber’s disease.