Movofen DS Tablets 2018-09-09T13:32:12+00:00

Acelofenac     –     50 mg

Paracetamol   –  250 mg

Each box contain 60 ml Bottle

Aceclofenac

It is non-steroidal anti-inflammatory drug. It is mainly used to relieve pain and inflammation occurring in rheumatoid arthritis.

Paracetamol  

It is a pain reliever and antipyretic properties. It is mainly used for headache and other minor pains.

  • Fever
  • Pain
  • Ankylosing spondylitis
  • Arthritis
  • Blocks COX which causes relief in swelling and inflammation
  • Blocks the substances in the body which causes pain and inflammation

Paracetamol

Paracetamol is a weak inhibitor for prostaglandin synthesis. It decreases the PG concentration but does not produce action against inflammation in arthritis.

Aceclofenac

It is having higher anti-inflammatory activity. It acts by blocking the action of substances in the body called as COX.

Both the drugs produce similar mechanism of actions

Paracetamol

Absorption

It is rapidly absorbed from the GI tract with the volume of distribution about 50L.

Distribution

It is metabolized in liver into its toxic and non-toxic products.

Excretion

About 85-90% of the drug is excreted in urine.

Aceclofenac

Absorption

The drug is rapidly absorbed into the body with approximately 100% bioavailability.

Distribution

The plasma protein binding of the drug is near to 99.7% and the drug is distributed in synovial fluid

Excretion 

About two-third of the drug is excreted in the conjugated form in urine.

  • Severe hepatic impairment
  • Hypersensitivity to acetaminophen
  • Patients with malnutrition and renal impairment
  • GI disturbances
  • Hepatic impairment
  • Alcohol depending patients
  • Hypertension or cardiac patients
  • Regular monitoring of renal and hepatic functions

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