Nervoba Forte

Composition

Methylcobalamin  –  1500 mcg
Alpha Lipoic Acid  –   100 mg
Folic Acid   –   1.5 mg
Pyridoxin HCl   –   3 mg
Benfotiamine   –   100 mg

Packing

Each box contain 3 Alu-Alu strips of 10 capsules

Product Description

Nervoba Forte capsule is the combination of methylcobalamin, alpha lipoic acid, folic acid, pyridoxine and benfotiamine. Methylcobalamin is a essential nutrient for neurons and alpha lipoic acid is an antioxidant which protects the neurons from oxidative stress.

Indication
  • Lowes the homocysteine levels
  • Reduces the risk of atherosclerosis
  • Prevents plaque
  • Benfotiamine have antioxidant capacity
  • Prevents DNA damage
  • Diabetic nerve pain
Mechanism of action

It reduces the excess biosynthesis and accumulation of variety of glucose metabolites. Benfotiamine causes increase in tissue levels of thiamine diphosphate which cause increase in transketolase activity. Methycobalamine causes transfer of methyl group for the regeneration of methionine from homocysteine. It acts as a cofactor for enzyme methionin synthase. In cases of anemia it causes the production of erythrocytes by nucleic acid synthesis in bone marrow.

Pharmacology

Methylcobaalmin
Absorption The drug is well absorbed in the body with peak concentration achieved after 3hrs.
Distribution After oral administration it is well distributed
Excretion The drug is excreted through urine.
Benfotiamine
Absorption It is well absorbed in body and dephosphorylated by cells which is having an ecto-alkaline phosphate to lipid soluble S-benzoylthiamine.
Excretion The drug follows urine albumin excretion

Contraindications
  • Hypersensitivity to any of the ingredient in the preparation
  • Sensitive reactions
  • Anaphylactic reaction
Precautions
  • Polycythemia rubra vera
  • Megaloblastic anemia
  • Cobalt or cobalamin allergy
  • Leber’s disease.