3x10 Alu-Alu

Nervoba Ala contains methylcobalamin, alpha lipoic acid, folic acid and pyridoxine phosphate.

Methylcobalamin

It is a form of vitaminB12. It is a cobalamin which differs from cyanocobalamin. The cyanide group is replaced by methyl group in methylcobalamin. Octahedral cobalt III is present in the centre.

Alpha lipoic acid

It is an antioxidant and is used for diabetes and nerve-related synmptomsof diabetes including burning, pain, and numbness in the legs and arms. High doses of alpha-lipoic acid are approved in Germany for the treatment of these symptoms.

Folic acid

It is also called as folate which is B vitamin. It is mainly used in food supplement industry. When administered in the body it is converted to dihydrofolate to tetrahydrofolate and to its derivatives.

Pyridoxine phosphate

It is a form of vitamin B6

• Neuropathic pain
• Anxiety disorder
• Reduces the haemocysteine levels
• Reduce the risk of atheriosclerosis
• Prevent LDL concentration
• Prevents induction of DNA damage
• Insomnia
• Skin disorders
• Diabetic nerve pain

methylcobalamin

It is the active form of vitamin B12 which a water soluble vitamin. It functions as to transfer methyl group for the regeneration of methionine from homocysteine. It acts as a cofactor for enzyme methionin synthase. In cases of anemia it causes the production of erythrocytes by nucleic acid synthesis in bone marrow.

Methycobalamin

Absorption

The drug is well absorbed in the body with peak concentration achieved after 3hrs.

Distribution

After oral administration it is well distributed

Excretion

The drug is excreted through urine.

• Decreases the GI absorption with neomycin
• Reduces the serum concentrations of oral contraceptives

• Polycythemia rubra vera
• Megaloblastic anemia
• Cobalt or cobalamin allergy
• Leber’s disease.