Each box contain 20 blister strips of 10 tablets

Nimesulide, the active ingredient in Nicare DS Tablets, is renowned for its dual action in managing pain and inflammation. This medication works by inhibiting specific enzymes responsible for the production of prostaglandins, which are key contributors to pain and inflammation.  It is designed for those seeking a reliable and fast-acting solution to various conditions such as musculoskeletal pain, osteoarthritis, and other inflammatory disorders. We offer this product under the brand name Nicare DS Tablets

• Relief of pain associated with acute musculoskeletal disorders
• Management of inflammatory conditions such as osteoarthritis
• Symptomatic treatment of primary dysmenorrhea
• Control of postoperative pain and inflammation

Nimesulide, a nonsteroidal anti-inflammatory drug (NSAID), exerts its effects through the inhibition of cyclooxygenase-2 (COX-2) enzyme, leading to the suppression of prostaglandin synthesis. By modulating these inflammatory mediators, Nicare DS Tablets provide relief from pain and inflammation.

Absorption:

Nimesulide is well-absorbed after oral administration, allowing for efficient bioavailability and rapid onset of action.

Distribution:

The medication is distributed throughout the body, targeting sites of inflammation and exerting its anti-inflammatory effects.

Excretion:

Nimesulide undergoes hepatic metabolism, forming various metabolites. The drug and its metabolites are primarily excreted through the urine and feces.

• Known hypersensitivity to Nimesulide or any of the tablet's components
• History of gastrointestinal bleeding or perforation related to previous NSAID use
• Severe hepatic impairment

Before using Nicare DS Tablets, consider the following precautions:

• Caution in patients with renal impairment
• Avoid use in patients with active peptic ulcers
• Monitor for signs of gastrointestinal bleeding during treatment
• Use with caution in elderly patients

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